Diabetes Treatment | Emcell Clinic
EmCell clinic is a medical center founded in 1994. In all these years, we treated thousands of patients from different countries and performed more than 6,000 transplantations of fetal stem cells. The treatment methods developed and used in the clinic helped to save and prolong our patients' lives, restore different organs and tissues and achieve positive results in treating diseases and conditions that were considered incurable.
Сonditions and diseases We Treat
- AIDS/HIV
- ALS
- Alzheimer's Disease
- Anemia
- Anti-Aging Treatment
- Arterial Hypertension
- Cancer
- Diabetes Treatment
- Eye Diseases
- Idiopathic Encephalopathy
- Ischemic Heart Disease
- Liver Diseases
- MD Treatment
- Multiple Sclerosis Treatment
- Parkinson Treatment
- Rheumatoid Arthritis
- SMA
- Ulcerative Colitis. Crohn’s Disease
Diabetes Treatment
We have developed an fetal stem cell transplantation-based method (excluding pancreatic beta-cells) for diabetes mellitus treatment. This method has proven to be effective for diabetes types I and II treatment and is protected by patents of many countries. Stem cell treatment of diabetes results in pronounced hypoglycemic effect, i.e. decrease of blood sugar level, allowing to reduce the dose of exogenous insulin by 50–70%. In more than half of cases diabetes treatment with fetal stem cells induces long-term clinical remission.
Symptoms of diabetes
Clinical manifestations of diabetes type 1 and 2 are similar but their intensity is different. In type 1 diabetes mellitus, the symptoms are more distinct and may develop quite rapidly over a few weeks. On the opposite, type 2 diabetes is often diagnosed accidentally.
Among the main symptoms of diabetes are
- frequent urination,
- persistent thirst due to significant water loss with urination
- dryness in the mouth
- increased hunger
- weight loss (and even cachexy) – in type 1 diabetes,
- weight gain in type 2 diabetes.
Secondary symptoms develop gradually and include
- itching of skin and mucous coats
- general weakness
- headaches and dizziness
- inflammatory skin involvement
- susceptibility to infectious diseases
- eyesight impairment
- decreased libido and sexual potency, etc.
Intensity of symptoms varies in each case. It depends on the duration of the disease, extent of insulin secretion decrease as well as on the individual peculiarities of the sufferer.
Diabetes-related complications
Stable blood sugar increase and impaired nutrition of body tissues cause a range of serious complications. Described are acute and chronic complications.
Among acute complications are
- diabetic ketoacidosis
- diabetic coma.
Chronic complications include
- diabetic macroangiopathy (damage of the large vessels)
- diabetic microangiopathy (damage of the small vessels such as arterioles, venules, and capillaries)
- diabetic neuropathy (nerve damage).
Other complications include
- retinopathy that can result in blindness
- renal damage – nephropathy with gradual development of renal insufficiency
- damage of the major arteries – atherosclerosis of cardiac and cerebral arteries
- soft tissues involvement such as trophic ulcers
- decreased immunity resulting in increased incidence of infectious-inflammatory processes.
Diabetes treatment with stem cells
We have developed an fetal stem cell transplantation-based method (excluding pancreatic beta-cells) for diabetes mellitus treatment. This method has proven to be effective for diabetes types I and II treatment and is protected by patents of many countries. Stem cell treatment of diabetes results in pronounced hypoglycemic effect, i.e. decrease of blood sugar level, allowing to reduce the dose of exogenous insulin by 50–70%. In more than half of cases diabetes treatment with fetal stem cells induces long-term clinical remission.
Indications for diabetes treatment with fetal stem cells
Stem cell treatment of diabetes is indicated at all stages of the disease. It is, however, the most effective in the cases of:
- new-onset insulin-dependent diabetes mellitus;
- diabetes mellitus complicated by diabetic glomerulosclerosis, chronic renal failure (grade 1 and 2) and anemic syndrome;
- labile course of diabetes mellitus;
- diabetes mellitus associated with infection complications and immune deficiency;
- presence of resistant to treatment trophic ulcers of the soft tissues;
- secondary sulfanilamide resistance and the need for patients with diabetes mellitus type II to transfer to insulin therapy.
Effects of diabetes treatment with fetal stem cells
Stem cell treatment of diabetes leads to significant improvement in patient’s condition. In some cases at the early stages of the disease, it may result even in the full recovery. After the stem cell therapy, diabetes mellitus patients report normalization of immunological and hematological indices, reduced manifestations of micro- and macroangiopathy and trophic disturbances, restoration of workability. In case of treatment the disease progression is hindered, and periods of remission become 2–3 times longer. Severity and frequency of diabetes complications decrease. Life quality and average life expectancy increase.
Major effects of diabetes mellitus treatment with stem cells are listed below.
Decrease of glycemia in patients with new-onset insulin-dependent diabetes mellitus
Within 2–3 months after the stem cell treatment, in 100% of cases the dosage of administered insulin gradually decreased. With the average initial insulin dosage at 0.76±0.06 units/kg/day, maximum dosage decrease amounted to 20–100% (41% on average), lasting for 14 to 90 days (59.0±4.3 days on average). In 65% of cases, diabetes treatment resulted in clinical remission with exogenous insulin dosage dropping to less than 0.4 units/kg/day, or insulin therapy completely discontinued. Remission lasted 5 to 14 months.
The syndrome of the early post-transplantation improvements
The syndrome of the early post-transplantation improvements includes weakness decrease, restoration of work capaсity, appetite and sleep. The syndrome is observed in 63% of cases.
Improvement of psycho-physiological condition
The syndrome of psycho-physiological changes includes improvement of thinking and mental capacity, inburst of energy, disappearance of anxiety, depression decrease, etc. The syndrome has been noted in 48% cases.
Immunity reconstruction
Diabetes treatment with fetal stem cells leads to restoration of immunological parameters. Lymphocyte count, T-lymphocytes and subpopulations of T-lymphocytes normalize. B-lymphocytes count decreases by 30–60%. The immunocorrecting effect lasts for 3 to 8 months.
Reconstitution of hematopoiesis
Within 1–1.5 months after the stem cell treatment of patients with diabetic glomerulosclerosis complicated by chronic renal failure (I, II and III degrees) and anemic syndrome, restoration of hematopoiesis, normalization of erythrocyte count and hemoglobin were observed. This effect is maintained up to 12 months.
Improvement of dystrophic disorders and trophic disturbances
After the transplantation of fetal stem cells, trophic ulcers disappear, microcirculation improves, and infectious skin lesions, fungus dermatitis, cutaneus lychenisation and lipoatrophic lesions decrease.
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