Welcome to Stem Cell Therapy in Frankfurt, Germany
Stem Cell Therapy in Frankfurt, Germany focuses on the potential vascular origin of multiple sclerosis and the demand by MS-patients for treatment. Because of the novelty of CCSVI, with few studies being available to assess long term outcomes, our primary goal is to avoid harm to patient and improve his/her life.
To achieve this goal we have formed collaboration between experts in the field of diagnostic imaging and vascular intervention who each are linked into an international network of specialists. This guarantees the highest level of proficiency in the diagnosis and treatment of CCSVI, the avoidance of negative side effects and complications and the participation in the rapid exchange of expert knowledge.
What is CCSVI?
The close spatial relationship between demyelization plaques and venous vessels on which CCSVI based, was postulated before 1980s as also the link between venous outflows disorders in the brain and the development back marks of MS.
Multiple sclerosis (MS) has been considered for many years to be an autoimmune disease, but recent research from Italy points out a possible new cause. According to the theory of Prof. Paolo Zamboni, a vascular surgeon from Ferrara, narrowings (stenoses) in jugular veins (neck) or the azygos veins returning the blood from the head to the heart, might be responsible for the development and the symptoms of MS (Multiple sclerosis).
The blood vessels constriction prevents blood flowing quickly enough (so-called reflux, where the blood vessels does not work properly and the blood flows into the brain again), with the consequence that iron is deposited in the brain (it could be seemed as white plaques visible on the MRI scan) causing autoimmune inflammation damaging the protective myelin nerve coating in the spinal cord and in the brain. This condition has become known as "CCSVI”: chronic cerebro-spinal venous insufficiency.
Widening of the stenotic (narrowed) veins increases the blood flow through them, thus, relieving the back-pressure and eliminating the inflammation, which is causing the damage to the brain, the spinal cord and protective myelin.
Identifying the problem
CCSVI investigation and diagnosis at CCSVI-Center (Frankfurt/Germany):
MRV-Screening - CCSVI Diagnostics following a modified and advanced Haacke Protocol.
In order to diagnose the CCSVI, CCSVI-Center in Frankfurt uses non-invasive or mini-invasive CCSVI investigations methods. Our experience and our collaboration with the vendors of medical equipment and medical scientists around the world helped us to improve the CCSVI Diagnosis protocols, in order to provide reliable and safe diagnostic for our patients.
Identification of CCSVI according to Zamboni is based on three methods:
1. Ultrasound examination (only head and neck)
The limitation of ultrasound is that it cannot assess the intrathoracic and abdominal venous system.
But it provides real-time information about blood flow dynamics, which is necessary to assess reflux in the lower internal jugular vein segment, that is important for the blood flow from the brain to the heart.
2. MR venography showing with color
The Haacke MR-protocol has been established as the standard for MR-venography and flow measurements in the work-up of CCSVI. It has, however, several drawbacks. Since MR-venography is carried out without breath holding and without cardiac gating, the azygos vein, that drains the blood from the spinal cord, cannot be depicted with sufficient accuracy on MRI
2. Catheter venography under fluoroscopy
Catheter venography or venogram, as a specialized form of angiography, is a medical imaging technique used to image the inside of blood vessels. This is traditionally done by injecting a contrast agent into the blood vessel and imaging with an X-Ray based technology such as fluoroscopy.
During catheter venography, a long, thin, flexible plastic tube (catheter) is inserted into the body, usually through a vein in the groin. The catheter is then threaded through the vascular system to the area requiring examination. A contrast dye is injected through the catheter and a rapid series of x-rays is taken, offering a detailed look at the specific blood vessels under the question.
If you want to know more about the treatments and procedures offered by Stem Cell Therapy in Frankfurt, Germany, please contact us!