Mesenchymal Stem Cell Therapy for Joints at Longevity Medical Institute®, San Jose del Cabo, Mexico

What Are Mesenchymal Stem Cells?

• Mesenchymal stem cells (MSCs) are remarkable, multi-functional repair cells that exist naturally in the human body. They are known for their ability to sense damage, regulate inflammation, and release a therapeutic toolkit of healing molecules.

• At Longevity Medical Institute®, we use ethically sourced placental and umbilical MSCs—which are highly potent, immune-compatible, and rich in regenerative potential. These cells function like biological command centers, orchestrating tissue healing in complex, responsive ways.

• When placed into damaged joints or connective tissue, MSCs interact dynamically with the injury site, stimulating regeneration, reducing inflammation, restoring structure, and preventing long-term disability. Unlike medications that mask symptoms, Stem Cell Therapy for Joint Pain in San Jose Del Cabo Mexico works with the body’s own intelligence—rebuilding the very tissue that pain and disease have worn away.

• Subtle tears in tendons or ligaments

• Fluid accumulation in joint spaces

• Inflammation and restricted blood flow

• Cartilage thinning or surface irregularities

• Scar tissue buildup

With this live visual data, we can diagnose with surgical-level precision—without invasive procedures or guesswork. Just as importantly, we use this same ultrasound technology to guide the injection itself, ensuring maximum accuracy and safety.

• Using our Sonosite SII in real-time, we can visualize the needle as it enters the body, adjusting its trajectory to reach the precise layer where regeneration is needed.

• Whether we are injecting into the cartilage of the knee, a torn rotator cuff tendon, or a worn-out ligament in the hip, the goal is always the same: place the MSCs exactly where they can do the most good.

• This level of accuracy is essential. With precision guidance, the cells are delivered into the biologically active zone, enhancing stem cell retention, engraftment, and therapeutic effect—setting the stage for a successful recovery.

Phase 1: Environmental Sensing and Attachment

MSCs detect distress signals (low oxygen, inflammation, etc.) which cues them to begin the repair process.

Phase 2: Secretion of Healing Factors

After attaching, MSCs act like living pharmacies, releasing bioactive compounds that reduce inflammation (e.g., IL-10) and stimulate regeneration (e.g., Growth factors like IGF-1, VEGF).

Phase 3: Remodeling and Regeneration

MSCs stimulate the regeneration of functional tissue. Local cells are activated, scar tissue begins to dissolve, and new structural proteins are synthesized.

Repairing the Musculoskeletal System: Tissue-by-Tissue Healing

• Cartilage Repair with Stem Cells in Los Cabos Mexico: MSCs stimulate type II collagen and proteoglycan production, inhibit cartilage-degrading enzymes, rebuild joint surfaces, and activate chondrocytes—leading to smoother movement and reduced pain.

• Tendons & Ligaments: They regenerate tenocytes, realign collagen fibers, improve tensile strength, and encourage collagen synthesis for stronger, more stable joints.

• Muscle & Bone: MSCs activate satellite cells, reduce fibrosis, and activate osteoblasts, remodeling bone and improving microcirculation.

• Scar Tissue: MSCs break down fibrosis and reorganize the Extracellular Matrix (ECM)—softening old injuries and restoring flexibility.

• Knees: Osteoarthritis, patellar tendonitis, ligament instability

• Hips: Labral tears, bursitis, avascular necrosis

• Shoulders: Rotator cuff tears, frozen shoulder

• Elbows & Wrists: Tendon overuse, epicondylitis, carpal tunnel

• Spine & SI Joint: Facet arthritis, disc degeneration, SI dysfunction

Timeline of Results:

• First few days: Mild soreness possible

• 2–4 weeks: Early relief and reduced stiffness

• 4–12 weeks: Ongoing regeneration

• 3–6 months: Full structural improvements

• Will I need multiple injections? Depends on damage extent; some need 1, others 2–3 spaced sessions.

• How long do results last? Months to years, depending on tissue regeneration.

• Are there side effects? Minor soreness or swelling possible; long-term effects are rare.

• Can this help me avoid surgery? Yes—many patients avoid replacements or reconstructions.

• Is it safe? Yes—ISO-certified cells under COFEPRIS oversight ensure safety.

Important Disclosure

In San Jose del Cabo (B.C.S), Mexico, where we conduct these treatments, our clinic operates under the oversight of COFEPRIS, Mexico's equivalent of the U.S. FDA. While approved by COFEPRIS, our therapies are not FDA-approved in the U.S. Patients should review all information, consult their physicians, and make informed decisions prior to treatment.

Disclaimer

The information provided is for informational purposes only and does not constitute medical advice. Therapies are subject to regional regulations and may not be available everywhere.