Pre-implantation Genetic Screening (PGS) in Cairo, Egypt

Is the PGS procedure safe for the embryo?

Yes, PGS is considered safe when performed by skilled embryologists. The biopsy is typically taken from the trophectoderm (the outer layer of cells that eventually forms the placenta) at the blastocyst stage (Day 5 or 6). This means the inner cell mass, which becomes the baby, is left untouched. Modern clinics in Cairo use laser-assisted biopsy techniques, which are minimally invasive. While there is a theoretically small risk of damage (less than 1%), the vast majority of embryos survive the biopsy and freezing process without issues.

How much does PGS cost in Cairo compared to the U.S.?

The cost savings are substantial. In the U.S., a full IVF cycle with PGS testing can range from $20,000 to $30,000. In Cairo, the same procedure, using comparable technology and medication, typically costs between $4,000 and $7,000. These lower costs are due to the exchange rate and lower overhead expenses in Egypt, not a lack of medical quality. This affordability allows many couples to attempt multiple cycles if necessary, which is often cost-prohibitive in Western countries.

Does PGS guarantee a pregnancy?

PGS does not "guarantee" a pregnancy, but it significantly increases the likelihood of a successful implantation and live birth. By transferring only genetically euploid (normal) embryos, you bypass the most common cause of IVF failure: chromosomal abnormalities. This is especially beneficial for women over 35 or those with a history of recurrent miscarriages. It essentially reduces the "time to pregnancy" by avoiding the transfer of embryos that would inevitably fail to implant or result in miscarriage.

What specific disorders does PGS check for?

PGS (or PGT-A) primarily screens for aneuploidy, which involves checking if the embryo has the correct number of chromosomes (46). It detects abnormalities such as Down Syndrome (Trisomy 21), Edwards Syndrome (Trisomy 18), Patau Syndrome (Trisomy 13), and Turner Syndrome. If you are known carriers of a *specific* genetic disease (like Cystic Fibrosis or Thalassemia), a different test called PGT-M (Pre-implantation Genetic Testing for Monogenic disorders) would be required, which is also widely available in Cairo.

How long do I need to stay in Cairo?

A typical IVF cycle with PGS requires a stay of approximately 15 to 20 days. This covers the ovarian stimulation phase, egg retrieval, and sperm collection. Because the genetic testing of the biopsy usually takes 1-3 weeks, most clinics perform a "Frozen Embryo Transfer" (FET). This means you would return home after retrieval and come back to Cairo a month or two later for the transfer, or stay for an extended period. Your specialist will create a customized schedule for you.

Is gender selection allowed in Egypt?

Yes, gender selection (often called family balancing) is legal and widely practiced in Egypt. Since PGS analyzes the chromosomal makeup of the embryo (XX for female, XY for male), the gender is identified during the screening process. Parents can opt to transfer embryos of a specific gender if they are genetically healthy. It is important to discuss this openly with your fertility specialist during the consultation to understand the ethical guidelines and clinic-specific protocols.

What is the success rate of IVF with PGS in Cairo?

Success rates in top Cairo clinics are comparable to leading international centers. For women under 35, success rates per transfer with a PGS-tested euploid embryo can reach 60-70%. For women over 40, utilizing PGS significantly improves live birth rates compared to standard IVF, as it prevents the transfer of abnormal embryos that would fail to develop. However, individual success depends on factors like ovarian reserve and uterine health.

Are the doctors in Cairo qualified?

Absolutely. Egypt has a very strong medical education system, particularly in gynecology and obstetrics. Many of the top fertility specialists in Cairo hold certifications or have completed fellowships in the UK (RCOG), USA, or Germany. They are frequent speakers at international fertility conferences (ESHRE, ASRM). You should look for doctors with established track records and clear board certifications, which PlacidWay verifies for all listed providers.

Is it safe to travel to Cairo right now?

Cairo is a major tourist destination welcoming millions of visitors annually. The areas where major medical centers are located (such as Maadi, Heliopolis, and New Cairo) are upscale, safe, and well-developed. As with any major metropolis, standard travel precautions apply. PlacidWay partners with clinics that offer chauffeur services and assistance with accommodation in safe, tourist-friendly zones to ensure your peace of mind.

What happens if no normal embryos are found?

If PGS results show that all embryos are aneuploid (abnormal), the transfer will be cancelled to avoid a failed cycle or miscarriage. While emotionally difficult, this information is valuable as it prevents the emotional and financial cost of a failed transfer. Your doctor will review the results to understand if the issue is egg quality, sperm quality, or random chance, and will propose a modified protocol for a future cycle to improve outcomes.

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