Dr. Chiara Maria Grana MD PhD, Nuclear Medicine Specialist - Milan, Italy

 

Experience:

April 2014 - Present: Director of the Division for Nuclear medicine at IEO, Milan, Italy

November 2013 - April 2014: Acting Director of the Division for Nuclear medicine at IEO, Milan, Italy

July 2001 - October 2013: Deputy Director of the Division for Nuclear medicine at IEO, Milan, Italy

1995 - 2001: Asisstant of the Division for Nuclear medicine at IEO, Milan, Italy

 

Clinical Activitiy: 

Dr. Chiara Maria Grana works in the fields of:

• Radiometabolic therapy in thyroid diseases

• Radioimmunotherapy with Beta emitters in brain tumors and non-Hodgkin lymphomas 

• Radionuclide receptor theapy

• Diagnosis with radiopeptides labelled Beta transmitters in endocrine malignancies

• Traditional nuclear medicine techniques

• Treatment of bone metastases 

Research Activity: 

• Brain and Haematological Malignancies: Non-Hodgkin's Lymphoma with Zevalin, by coordinating radioimmunotherapy protocol
• Clinical investigator in different radioimmunotherapy protocol
• Collaboration in the field of radio-labelled peptides in endocrine malignancies
• Active contribution to the development of different aplications of lymphoscintigraphy and of antibodies with the avidin-biotin system in patients with solid tumors (ovarian, glioma, breast, colon and melanoma)
• She has experience in GCP trials

 

Past Clinical & Research Activity:

• 1994 - Attending physician at the Spedali Civili - Brescia - Radiometabolic Division;
• 1990-1994: Fellowship Istituto Scientifico San Raffaele, Milan, Italy; 
• 1989 - Visiting student at the Department of Internal Medicine of the University of Nijmegen, Netherlands;
• 1988 - 1990: Student at Istituto Scientifico San Raffaele, Nuclear Medicine Division in Milan, Italy
• 1988 - Visiting student at the State Hospital Bratislava, Slovakia
• 1986- 1988: Student at the Ospedale Niguarda Ca' Granda General Medicine Division, Milan, Italy.

 

Therapeutic Applications of Nuclear Medicine in Oncology:

• Receptor radionuclide therapy with stomatostatin and bonbesin analogues, radiolabelled with beta-transmitters;
• Translational research applied to radio peptide therapy;
• Radioimmunotherapy with beta-emitters by means of avidin-biotin system; loco-regional and systemic administration in brain tumors and ovarian carcinoma;
• Radioimmunotherapy with antibodies radiolabelled with beta-emitters in NHL and ovarian carcinoma;
• Internal dosimetry in radionuclide diagnosis and therapy;
• Radionuclide therapy of differentiated thyroid cancer and hyperthyroidism with 131I;
• Radionuclide therapy in bone metastases.

 

Diagnostic applications of Nuclear Medicine in Oncology:

• Receptor scintigraphy with radiolabelled peptides;
• Radioimmunoscintigraphy with avidin-biotin system;
• PET/CT in Oncology;
• Laboratory Nuclear Medicine in Tumor diagnosis;
• Routine diagnostic examinations.

 

Additional Information:

She is the person in charge of the Quality process and also collaborated in the ISO 9001 Certification process for the Division of Nuclear Medicine at IEO, Milan, Italy.

Congresses – Constantly attending national and international congresses in the field of Nuclear Medicine & Oncology

Publications:

• More than 50 articles on international peer-reviewed journals
• 5 invited book chapters
• 9 publications in national journals
• Abstracts in international and national journals.