IAKENTRO Egg Donation Agency IAKENTRO Egg Donation Agency

Athens, Greece

THESSALONIKI 4 Ag. Vasiliou St. Postal Code: 54 250 Call Centre: +30 2310 330519
ATHENS +30 2106 179340 4 Fragkokklisias St. Postal Code: 15 125 Maroussi

Focus Area: IAKENTRO Egg Donation Agency | In Vitro Fertilisation | Infertility | IVF Treatment | Surrogacy | Intra-Uterine Insemination | Embryo Freezing | Athens, Greece Best In Vitro Fertilisation Hospital, Infertility Center, Affordable  IVF Treatment Clinic, Surrogacy Treatment, Intra-Uterine Insemination Cost, Top Qualified Embryo Freezing Doctor, Benefits of  In Vitro Fertilisation, Athens, Greece

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IAKENTRO Egg Donation Agency | We Deliver Solutions To Your Problem

Welcome

Welcome to Iakentro. Here you can find out about us, how we can meet your needs and obtain detailed information about the services we provide, with commitment and consistency. In our effort to fully meet your needs, we have set up innovative and specialized units in a respectful and loving environment for people.

We provide services in perfect conditions demonstrating responsibility and professionalism, aiming  at covering  all needs of  both men and women in fertility diagnosis and treatment.

Apart from high-quality services  you will also find people who responsibly and willingly perform what is the best for you, minimising potential risks and maximising chances for the final result.
 

In a state-of-the-art medical center for men and women, we have set up innovative and specialized units in the fields of IVF, maternal-fetal medicine, genetics and molecular biology.

About IAKENTRO

IAKENTRO is a new, guaranteed proposal of an integrated Gynaecology and Obstetrics unit in the Balkans, supported by cutting-edge technological equipment, experienced human resources and internationally renown partners.

Our main concern being humane approach and psychological support to couples, combined with best results, both in prevention and treatment.

The IAKENTRO IVF unit was first created in Thessaloniki in 1998 and since then has been providing its services, offering modern solutions to all infertility problems.

The high-quality operation of our centre, the ongoing training of our staff, combined with high success rates and affordable treatment, have been a pole of attraction for many couples from abroad. Therefore, in the last 8 years visitors come not just from all over Greece, but also from various European countries, whom we provide with fine accommodation and services. During their stay in Thessaloniki, the medical staff, translators and programme coordinators are here to solve any problem that might arise.

Iakentro Units

In our effort to provide services of advanced medicine to as more couples facing infertility as possible, we expand our activities to various cities of the Balkans, establishing infertility centres.

  • THESSALONIKI (GREECE) 1998
  • ATHENS (GREECE) 2007
  • TIRANA (ALBANIA) 2005
  • SOFIA (BULGARIA) 2008

Assisted Reproduction

  • Intrauterine Insemination
  • Assisted Reproduction (IVF-ICSI-FNA-TESE)
  • Male Infertility Treatment
  • Oocyte Donation
  • Sperm Donation
  • Embryo Donation
  • Gestational Surrogacy
  • Sperm Diagram | Sperm Enrichment
  • Sperm DNA Analysis (DNA Fragmentation)
  • In Vitro Maturation Of Oocytes (IVM)
  • Biochemical Assessment
  • Assisted Hatching
  • Preimplantation Genetic Diagnosis
  • Blastocyst Embryo Transfer
  • Oocyte Cryopreservation
  • Embryo Cryopreservation - Vitrification
  • Ovarian Tissue Cryopreservation
  • Sperm Cyropreservation | Sperm Bank
  • Psychological Support

Our Services

  • OOCYTE DONATION PROGRAM
  • Molecular Biology and Genetics
  • Maternal-Fetal Medicine
  • Reproductive System Surgery

 

Details

In our effort to provide services of advanced medicine to as more couples facing infertility as possible, we expand our activities to various cities of the Balkans, establishing infertility centres.

  1. THESSALONIKI (GREECE) 1998
  2. ATHENS (GREECE) 2007
  3. TIRANA (ALBANIA) 2005
  4. SOFIA (BULGARIA) 2008

THESSALONICA

Since 1998, IAKENTRO, Thessaloniki, have been settled in a modern five-floored building, where the more specialized techniques of in vitro fertilisation, maternal-fetal medicine, genetics and molecular biology have been applied.

4 Ag. Vasiliou St.
Postal Code: 54 250
Thessaloniki
Call Centre: 00302310330519 (from 9:00-16:00)
                    00302106179340 (from 16:00-21:00)

ATHENS

4 Fragkokklisias St.
Postal Code: 15 125
Maroussi
Call Centre: +30 210 6179340

TIRANA

The assisted reproduction unit of Iakentro operates in Tirana since 2005, autonomously providing all IVF techniques.


SOFIA

Coming Soon

 

Treatments

Assisted Reproduction

  • Intrauterine Insemination: Insemination may be the first step for infertility treatment. The method is simple and affordable. The success rate in homologous insemination reaches 10-15%, while in cases of heterologous insemination, the rate is higher (~25%).
  • Assisted Reproduction (IVF-ICSI-FNA-TESE): In vitro fertilization (IVF) is currently the definite choice of infertility  treatment when other,  simpler methods of assisted reproduction are not able to  provide solutions (i.e. women with closed or destroyed fallopian tubes). ICSI (Intra-Cytoplasmic Sperm Injection) is a type of IVF with micro-fertilization. It is indicated in cases of male infertility and may be  combined with  TESE or FNA (Testicular Sperm Extraction - Fine Needle Aspiration).
  • Male Infertility Treatment: Andrology unit of IAKENTRO offers both diagnosis and treatment in male infertility.
    Male infertility covers a wide range from  complete absence of germ cells till mild  forms of astheno-oligo-teratospermia.
  • Oocyte Donation: The oocyte donation program of IAKENTRO was established in 1989, when we achieved the first pregnancy from oocyte donation in Greece, which resulted in the birth of full-term twins. This success has been the trigger for the initiation of a special oocyte donation program, with the participation of volunteer donors.
  • Sperm Donation: Sperm donation is the only solution in cases when  methods  for the treatment of male infertility (IUI, ICSI, FNA, TESE) cannot be applied.
    Sperm donors, 18-35 years of age, are examined by an Internal Medicine Physician and are subject to a number of laboratory tests.

  • Embryo Donation: This is indicated for couples where both partners (man and woman) are not able to undergo infertility treatments with their own gametes (oocytes and sperm).
  • Gestational Surrogacy
  • Sperm Diagram | Sperm Enrichment: This test checks the quality of semen, identifying sperm concentration, motility and morphology.
  • Sperm DNA Analysis (DNA Fragmentation): Recent studies have shown that sperm DNA fragmentation, which is an indication of increased sperm apoptosis percentage, might be the cause for IVF failures. These studies have demonstrated  that, in semen samples in which the percentage of sperm with DNA damage is higher than 20%, the chances to achieving  pregnancy are significantly reduced.
  • In Vitro Maturation Of Oocytes (IVM): In  cases of IVM, ovaries are only mildly stimulated. Oocytes are then collected, however, final stage of maturation takes place at the laboratory. Finally, fertilization and embryo transfer  follows, like in an  IVF cycle. IVM is a method which may provide solutions in certain cases where  administration of hormones to stimulate the ovaries is difficult or contraindicated.
  • Biochemical Assessment: This is a new technique  assessing  the ability of embryos resulting from IVF  to implant  in the endometrium.
    Results of recent studies have shown that embryos demonstrating sHLA-g protein above certain levels,  have higher implantation rates.
  • Assisted Hatching: At the early stages of development, embryos are covered by an outer layer, the transparent zone, which protects embryonic cells. This zone is partially diluted and the embryo “hatches” when it reaches the uterus, so that it can be implanted in the endometrium and keep developing. However, in certain cases of IVF, it is considered necessary to assist hatching by reducing the transparent zone width. The procedure is performed on the day of embryo transfer using a special laser.

  • Preimplantation Genetic Diagnosis: In this  procedure, the  genetic material of embryos is checked prior to embryo transfer. This method constitutes a combination of in vitro fertilization and special genetic analysis  techniques.
  • Blastocyst Embryo Transfer: Culture media are continuously improved   to adapt  in  the best way to the embryo’s needs in different stages of development and culture conditions in incubators are continuously  optimized Thus, recent advances  have allowed us embryo   culture until the blastocyst stage.
  • Oocyte Cryopreservation: Oocyte vitrification was first announced in 1987; however, until recently it was an experimental procedure, since gestation rates were disappointing due to the low survival rates of embryos. Recently, an improved vitrification method has been  developed, based on faster vitrification, which ensures a higher oocyte survival rate (up to 100%) and a pregnancy rate of 40%.
    Vitrification of unfertilized oocytes will bring revolution in the treatment of assisted  reproduction as women will be able to keep their oocytes vitrified for a long period of time.
  • Embryo Cryopreservation - Vitrification: This method is used in the following cases:
    When embryo transfer cannot be performed for some reason (e.g. hyperstimulation of the ovaries);
    When there are excess embryos with normal development and morphology after the transfer and can be  used in a subsequent  cycle.
  • Ovarian Tissue Cryopreservation: Ovarian tissue cryopreservation is, currently at experimental stage. It may be applied in women who will undergo chemotherapy or surgical removal of ovaries. During this procedure, solid parts of the ovary containing several immature follicles are removed by laparoscopy and are frozen.

  • Sperm Cyropreservation | Sperm Bank: Sperm cryopreservation is a widespread method, frequently applied with great success as  survival rates of spermatozoa after thawing are very high.
  • Psychological Support: In vitro fertilization has set new grounds in the treatment of infertility, currently demonstrating high success rates. Nevertheless, it remains a difficult procedure causing psychological stress. Each person reacts differently to infertility. It is normal that any of the partners  attempting IVF may  fear the unknown medical action and feel insecure about the impending procedure.  Very often, couples wish to share those feelings with a specialist who will support them, in strict confidence.

Our Services

  • OOCYTE DONATION PROGRAM
  • Molecular Biology and Genetics
  • Maternal-Fetal Medicine
  • Reproductive System Surgery

 

Qualifications



Nikos Prapas
 
Professor of Obstetrics - Gynaecology Aristotle University of Thessaloniki
 
He graduated from the Medical School of the Aristotle University of Thessaloniki and completed his specialization in Obstetrics-Gynaecology in 1983. In 1984, his interest in infertility led him to Italy where he was trained for one year on infertility problems (Hysteroscopy, Laparoscopy, Andrology, IVF), under the supervision of Professor Ettore Cittadini, one of the pioneers in the establishment of GIFT (gamete intra-Fallopian transfer) in Europe. In 1997 he attended the works of the Ultrasound in Obstetrics and Gynaecology department of the Yale University (USA) as a Fellow Visitor. Subsequently, he attended a refresher course at various pioneer IVF centres (Prof. Schoysman Belgium, Jones & Jones Institute, USA). He currently attends an ongoing refresher course at Jones & Jones Institute, in the context of a postgraduate degree in Clinical Embryology and Andrology. Mr. Nikos Prapas was among the pioneers who established transabdominal ultrasound-guided embryo transfer in IVF, while his work includes a large number of scientific publications on infertility.

Yannis Prapas

Assistant Professor of Obstetrics - Gynaecology
Aristotle University of Thessaloniki

He graduated from the Medical School of the Aristotle University of Thessaloniki and in 1984 he completed his specialization in Obstetrics-Gynaecology at the University Hospital of Alexandroupoli. His interest in infertility took him to Paris in 1985, where he observed the hysterectomies performed by J. Hamou for two months; subsequently he worked as a collaborating researcher on endometrial receptivity at the laboratory of A. Psychoyos at Ηopital Kremlin-Bicetre, where the first international papers on embryo implantation were published. He specialized on infertility problems and IVF in Bordeaux, France, where he worked for one year under the guidance of Alain Audebert and J.C.Emperaire. He attended a 6-month refresher course in Belgium, at the Andrology and IVF unit of professor Robert Schoysman. Ever since he has visited various renown IVF centres and in 1996 he attended the works of the Reproductive Endocrinology of the Yale University as a Fellow visitor, under the supervision of Professors Naftolin, D. Olive and E.Ε. Jones. Mr. Yannis Prapas has produced international literature and research related to intrauterine implantation during IVF.


Stella Prapa, MD , PhD

Microbiologist - Genetician

She graduated from the Medical School of the Aristotle University of Thessaloniki and in 1991 she completed her specialization in Microbiology. Her refresher courses started at the laboratory department for IVF at the Univeristy Hospital of Brussels, Belgium, “Genees – en Heelkundig Institut” under the supervision of Professor Schoysman. After her MD and PhD, her interest in Genetics directed her to refresher courses for 1.5 year in various centres in Italy, in Cytogenetics and Molecular Biology. She started refresher courses on cytogenetics in Palermo, Italy, at “Ospedale Vincenzo Cervello”, under the supervision of Dr. Orlandi, and then at the “Istituto Materno Infantile” of the University of Palermo under the supervision of Professor Cittadini; She continued with the Department of Hygiene and Microbiology at the University of Palermo, “Giuseppe d’ Alessandro” (being the reference centre of Salmonellosis in Central and Southern Italy), where she participated in a research on the molecular biology of enterobacteriaceae, supervised by Professor A. Nastasi. Her refresher training continued in Milan at the “Laboratorio di Ricerche Cliniche, Anatomia ed Istologia Patologica” in Molecular Biology under the supervision of Dr. Travi, and subsequently in Genova, at “Ospedali Galliera” under the supervision of Dott. Franca Dagna – Bricarelli, then at the private Genetics centre “Consultorio di Genetica – Genoma“ under the supervision of Dott. Baldi and Dott. Fiorentino, respectively, and finally at the cytogenetics laboratory of the “YALE University”, USA. Ever since, she has been systematically visiting and following up developments in Genetics, to obtain information for the diagnostics department of the Genetics laboratory.

Ms. Prapa has published numerous articles in scientific journals in Greece and abroad.


YANNIS PANAGIOTIDIS

Embryologist – Head of assisted reproduction laboratory

Yannis Panagiotidis was born and raised in Athens. In 1998 he graduated from the Biology Department of the Aristotle University of Thessaloniki. Since then he has been working as an embryologist at the assisted reproduction department of “IAKENTRO”. In the context of his training, he visited many laboratories in the USA and Europe, where he worked on all assisted reproduction techniques, but also issues related to fetal biopsy, PGD and vitrification of embryos and oocytes. He is now towards completion of his PhD theses on oocyte and embryo vitrification.


EVANGELIA KASAPI

Embryologist

Evangelia Kasapi was born and raised in Serres. She studies biology at Univesita Degli Studi di Siena in Italy. She worked on assisted reproduction and embryo co-culture with endometrial cells. In 2002 she returned to Greece when she joined IAKENTRO as an embryologist. She has been trained on IVF techniques. She specializes in fetal biopsy, PGD and embryo vitrification. She is now towards completion of her PhD on in vitro maturation.

 


MARIA GOUNDAKOU

Embryologist

Maria Goundakou was born and raised in Kavala. She studies biology at the Aristotle University of Thessaloniki and graduated in 2000. She immediately joined IAKENTRO where she works at the IVF laboratory. She has been trained on all assisted reproduction techniques (oocyte collection, sperm processing, microfertilisation, fetal biopsy, gamete and embryo freezing), as well as embryo vitrification and fetal biopsy. In 2006 she took a refresher course on human reproduction with the postgraduate department "Biology of Reproduction" of the Medical department of the University of Thessaly.

 


ACHILLEAS PAPATHEODOROU

Embryologist

Achilleas Papatheodorou was born and raised in Larissa. In 1999 he joined the Biology department of the Aristotle University of Thessaloniki and graduated in 2004. During the last year of his studies he worked on human reproduction biology. In 2004 he took a refresher course on assisted reproduction attending the Master of Medical Sciences in Assisted Reproduction Technology at the University of Nottingham for one year. In 2006 he joined the scientific team of “IAKENTRO” and now works at the IVF laboratory.


TATIA PASADAKI

Embryologist

Tatia Pasadaki was born and raised in Alexandroupolis. In 2001 she joined the department of the Aristotle University of Thessaloniki and graduated in 2006. In her diploma thesis she discussed the topic of developmental biology. During her postgraduate studies she was specialized in Preimplantation Genetic Diagnosis and Embryology in University College London. Since 2009 she is a member of the scientific team of “IAKENTRO” and works at the IVF laboratory. She is currently a PhD candidate in the field of andrology and male infertility.

 

Awards

Oocyte Bank

Preserving Female Fertility – Freezing the Biological Clock


The latest developments in the field of reproductive medicine guarantee the preservation of fertility for women who wish or need to do so. This involves the new revolutionary method of oocyte vitrification combined with rapid thawing. According to professor Nikos Prapas, who applies this new method at the IAKENTRO medical centre, the rate of viability is as high as 90%.

According to theprocedure followed, the oocytes are retrieved either following hormonal stimulation of the ovaries (freezing of multiple oocytes) or during the natural menstrual cycle (freezing of the oocyte that is naturally produced every month). When the woman wishes to become a mother, the oocytes will be thawed and the standard procedure of in-vitro fertilization will be followed (fertilisation and embryo transfer).

This method is applied to women of a young age, when their oocytes are still “young”, who wish to start a family at a later age due to their careers or other circumstances, in which case it is deemed necessary to preserve their fertility. In fact, the ageing of the ovaries begins gradually at the age of 34-37, and becomes more drastic from the age of 38 onwards. There are also other iatrogenic conditions that speed up the ageing of the ovaries, such as ovarian cancer, chemotherapy or radiation, and early menopause.

“By applying this method we are essentially freezing time and giving all women the opportunity to feel complete through child-bearing, even if their biological clock has already stopped ticking”, states Mr. Nikos Prapas.


Sub-fertility among ultra-thin women


According to recent studies, ultra-thin women face minor or major sub-fertility problems. This differs from the view widely accepted to date, i.e. that overweight women were those less likely to achieve pregnancy, either naturally or by in vitro fertilisation.  

The index indicating whether a woman is ultra-thin, of normal weight or obese is called Body/Mass Index (BMI) and it is calculated by dividing a person’s weight in kilos by the square of their height in metres (weight/height2). Women with a BMI of 14-18 are considered ultra-thin, with a BMI of 19-28 normal and with a BMI of 29-43 obese. Initially it was assumed that women with a low body weight were less likely to conceive due to low oestrogen production. This might have a negative impact on ovulation or even interrupt it, while also affecting endometrial thickness, and, consequently, the capacity for embryo implantation. However, it has been observed that body weight plays a role even in cases of women on hormonal treatment in preparation for in vitro fertilisation, which leads to the conclusion that the weight – sub-fertility correlation is not a matter of hormones.   

According to Professor Nikos Prapas (Obstetrician – Gynaecologist), “the most recent current view is that pregnancy may not be achieved due to embryo undernourishment, leading to implantation failure”. This is what Mr. Prapas concludes: “When a woman wishes to get pregnant, either naturally or following some form of sub-fertility treatment, she needs to look after her weight and maintain it within normal range, rather than trying to comply with social norms”.

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Thessaloniki

Athens

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